Hyaluronic acid is an acid mucopolysaccharide. It can be extracted from animal tissues after analysis and treatment, or from the biochemical reactions of bacteria to sugar.
can be used in medical industry, cosmetics and food industry according to the
In 2018, the
global sales volume of hyaluronic acid raw materials reached 500 tons,
including 230 tons for food grade applications, 250 tons for cosmetics and 20
tons for medical use. From 2014 to 2018, the compound annual growth rates of
food grade, medical grade and cosmetic grade hyaluronic acid were 29.4%, 22.0%
and 18.0% respectively. And it’s expected that in the next five years, it will maintain
a compound annual growth rate of 18.1%.
of raw materials is relatively concentrated. China is the largest supplier of
hyaluronic acid and the top five hyaluronic acid enterprises are all from
China. Bloomage Biotech is the number one hyaluronic acid supplier with the
market share of 36%, followed by Focuschem Biotech with the market share of 12%,
Fufeng Biotech with the market share of 10%, Dongchen Biotech with market share
of 8% and AWA Biopharm with the market share of 7%.
The major overseas
hyaluronic acid enterprises include Kewpie from Japan and (4%) and Contipro from Czech (4%). The sales market share of other domestic and overseas
enterprises is less than 4%, such as China's Topscience, Tiansheng Biological, Galaxy
Biopharma, etc., and overseas enterprises, such as Soliance from France, Bioland
from South Korea, Evonik from Germany, Shiseido from Japan's, etc., as well as
HTL from France and America's Lifecore that only focus on the production of
medical-grade hyaluronic acid.
In the past five
years, China's sales volume of hyaluronic acid raw materials rose from 189.2MT
tons in 2014 to 430 MT in 2018, seeing a compound annual growth rate of 22.8%.
However, China's hyaluronic acid raw materials are mainly concentrated in the
low value-added cosmetics and food grade, and the pharmaceutical grade raw
materials account for only 2.3% of total sales, much lower than the world
average of 14.3 %. Therefore the structure needs to be optimized and improved.